O-[[4-(三氟甲基)苯基]甲基]羟胺盐酸盐

O-[[4-(三氟甲基)苯基]甲基]羟胺盐酸盐 - Names and Identifiers

Name	O-[4-(Trifluoromethyl)benzyl]hydroxylamine hydrochloride
Synonyms	4-Trifluoromethylbenzyloxyamine hydrochloride O-[4-(TrifluoroMethy)benzyl]hydroxylaMine hydrochloride O-[4-(TRIFLUOROMETHYL)BENZYL]HYDROXYLAMINE HYDROCHLORIDE O-(4-Trifluoro-methyl-benzyl)hydroxylamine hydrochloride O-[4-(Trifluoromethyl)benzyl]hydroxylamine hydrochloride 1-[(AMMONIOOXY)METHYL]-4-(TRIFLUOROMETHYL)BENZENE CHLORIDE 1-[(AMINOOXY)METHYL]-4-(TRIFLUOROMETHYL)BENZENE HYDROCHLORIDE O-[[4-(Trifluoromethyl)phenyl]methyl]hydroxylamine hydrochloride 1-[(Aminooxy)methyl]-4-(trifluoromethyl)benzene hydrochloride, 4-[(Aminooxy)methyl]benzotrifluoride hydrochloride
CAS	321574-29-2

O-[[4-(三氟甲基)苯基]甲基]羟胺盐酸盐 - Physico-chemical Properties

Molecular Formula	C8H9ClF3NO
Molar Mass	227.61
Melting Point	325-238°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	IRRITANT
MDL	MFCD00231881

O-[[4-(三氟甲基)苯基]甲基]羟胺盐酸盐 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

O-[[4-(三氟甲基)苯基]甲基]羟胺盐酸盐 - Introduction

O-[4-(Trifluoromethyl)benzyl]hydroxylamine hydrochloride is an organic compound with the formula C8H8F3NO · HCl. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White or off-white crystalline solid
-Melting point: approximately 166-168°C
-Solubility: Low solubility in water, soluble in organic solvents such as ethanol and ether

Use:
- O-[4-(Trifluoromethyl)benzyl]hydroxylamine hydrochloride is a commonly used organic synthesis intermediate, commonly used in organic synthesis reaction of amino protecting agent, reducing agent and amino radical donor.
-It can be used to synthesize heterocyclic compounds, nitrogen-containing heterocyclic derivatives, amino compounds, etc.

Preparation Method:
The preparation of O-[4-(Trifluoromethyl)benzyl]hydroxylamine hydrochloride can be carried out by the following steps:
-Reaction of trifluoromethyl anisole with bromoacetate to give the corresponding acid ester compound.
-The acid ester compound is reduced by sodium borohydride to obtain trifluoromethylbenzoxylamine.
-Finally, trifluoromethylbenzoxylamine is reacted with hydrochloric acid to prepare O-[4-(Trifluoromethyl)benzyl]hydroxylamine hydrochloride.

Safety Information:
- O-[4-(Trifluoromethyl)benzyl]hydroxylamine hydrochloride are stored and used in accordance with general laboratory safety practices.
-Avoid contact with skin and eyes, wear protective gloves and goggles if necessary.
-Avoid inhaling the dust or gas of the solution, and use it in a well-ventilated place.
-storage should be placed in a dry, cool, ventilated place.

Last Update：2024-04-10 22:29:15